BDBM737124 7-(5-fluoro-2-(((3S,4R)-3-hydroxytetrahydro-2H-pyran-4-yl)amino)pyrimidin-4-yl)-2-(((3R,4R)-4-fluoro-3-hydroxypiperidin-1-yl)methyl)-1-isopropylquinolin-4(1H)-one & 7-(5-fluoro-2-(((3S,4R)-3-hydroxytetrahydro-2H-pyran-4-yl)amino)pyrimidin-4-yl)-2-(((3S,4S)-4-fluoro-3-hydroxypiperidin-1-yl)methyl)-1-isopropylquinolin-4(1H)-one::US20250136586, Example 84

SMILES CC(C)n1c(CN2CC[C@H](F)[C@@H](O)C2)cc(=O)c2ccc(-c3nc(N[C@@H]4CCOC[C@H]4O)ncc3F)cc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 737124   

LigandPNGBDBM737124(7-(5-fluoro-2-(((3S,4R)-3-hydroxytetrahydro-2H-pyr...)
Affinity DataIC50: 6.80nMAssay Description:Compounds disclosed herein were tested for inhibition of CDK4/Cyclin D1 or CDK6/Cyclin D3 kinase in an assay based on the time-resolved fluorescence-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2025
Entry Details
US Patent

LigandPNGBDBM737124(7-(5-fluoro-2-(((3S,4R)-3-hydroxytetrahydro-2H-pyr...)
Affinity DataIC50: 170nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2025
Entry Details
US Patent