BDBM737455 US20250136619, Compound I-5

SMILES C[C@@H]1COCCN1c1nc(N2CCOC[C@H]2C)c2ccc(-c3cccc(C(=O)NCCOCCOCCOCCOCCOCCOCCOCCOC/C=C/C(=O)N4CCC[C@@H](n5nc(-c6ccc(Oc7ccccc7)cc6)c6c(N)ncnc65)C4)c3)nc2n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 737455   

TargetTyrosine-protein kinase BTK(Human)
Halda Therapeutics OPCO

US Patent
LigandPNGBDBM737455(US20250136619, Compound I-5)
Affinity DataKd: <50nMAssay Description:Compounds were tested using a KdELECT assay. Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Halda Therapeutics OPCO

US Patent
LigandPNGBDBM737455(US20250136619, Compound I-5)
Affinity DataKd:  275nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1×binding buffer (20% SeaBlock, 0.17×PBS, 0.05%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent