BDBM738046 2-(7-cyclopropyl-6-((4-(4- cyclopropyl-1,1-dioxido-5-oxo- 2,3,4,5-tetrahydrothieno[2,3- f][1,4]thiazepin-7-yl)-5- (trifluoromethyl)pyrimidin-2- yl)amino)-3,4-dihydroisoquinolin- 2(1H)-yl)acetamide::US20250144094, Example 278

SMILES NC(=O)CN1CCc2cc(Nc3ncc(C(F)(F)F)c(-c4cc5c(s4)C(=O)N(C4CC4)CCS5(=O)=O)n3)c(C3CC3)cc2C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 738046   

TargetSerine/threonine-protein kinase ULK1 [1-649](Homo sapiens (Human))
Erasca

US Patent
LigandPNGBDBM738046(2-(7-cyclopropyl-6-((4-(4- cyclopropyl-1,1-dioxido...)
Affinity DataIC50: 5nMAssay Description:Table 4: ULK1 inhibitor potency was determined using the luminescent ADP Glo Kinase Assay (Promega), a universal ADP detection system that measures k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent