BDBM738179 Compound prepared in Example 6::US12297164, Example 6

SMILES Nc1cccc(CC(=O)Nc2ccc(-c3ccc(C(O)(C(F)(F)F)C(F)(F)F)cc3F)cc2)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 738179   

TargetNuclear receptor ROR-gamma(Human)
Guangzhou IMD Therapeutics Co.

US Patent
LigandPNGBDBM738179(Compound prepared in Example 6 | US12297164, Examp...)
Affinity DataIC50: 960nMAssay Description:Table 1: Experimental materials: target protein RORγ with the final concentration of 200 nM; experimental buffer (10×) MOPS (500 mM) PH 7.4, CHAPS (0...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Guangzhou IMD Therapeutics Co.

US Patent
LigandPNGBDBM738179(Compound prepared in Example 6 | US12297164, Examp...)
Affinity DataIC50: 5.17E+3nMAssay Description:Table 1: Experimental materials: target protein RORγ with the final concentration of 200 nM; experimental buffer (10×) MOPS (500 mM) PH 7.4, CHAPS (0...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent