BDBM738351 2,4,6-trifluoro- N-(5-(4-(8-(2- fluoroacryloyl)- 3,8- diazabicyclo [3.2.1]octan-3- yl)quinazolin-6- yl)-2- methoxypyridin- 3-yl) benzene- sulfonamide::US20250145589, Example 156

SMILES C=C(F)C(=O)N1C2CCC1CN(c1ncnc3ccc(-c4cnc(OC)c(NS(=O)(=O)c5c(F)cc(F)cc5F)c4)cc13)C2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 738351   

LigandPNGBDBM738351(2,4,6-trifluoro- N-(5-(4-(8-(2- fluoroacryloyl)- 3...)
Affinity DataIC50: 0.5nMAssay Description:The ADP-Glo™ kinase assay was used to assess the inhibition of PI3Kα with our compounds. The utilized proteins and assay reagents were obtained from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent