BDBM738739 2-(7,7-difluoro-2-((2S,3R)-3-hydroxy- 2-methylazetidine-1-yl)-6,7-dihydro- 5H-cyclopentadiene[d]pyrimidin-4- yl)-2-azaspiro[3.3]heptan-6- carboxylic acid::US20250145619, Example 31

SMILES C[C@H]1[C@H](O)CN1c1nc(N2CC3(CC(C(=O)O)C3)C2)c2c(n1)C(F)(F)CC2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 738739   

TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM738739(2-(7,7-difluoro-2-((2S,3R)-3-hydroxy- 2-methylazet...)
Affinity DataIC50: 134nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent