BDBM73920 MLS001173843::SMR000596364::US11634404, Compound 65::[4-[2-(4-methoxyphenoxy)ethyl]-1-piperazinyl]-(4-methoxyphenyl)methanone::[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]-(4-methoxyphenyl)methanone::[4-[2-(4-methoxyphenoxy)ethyl]piperazino]-(4-methoxyphenyl)methanone::cid_9268266
SMILES COc1ccc(OCCN2CCN(CC2)C(=O)c2ccc(OC)cc2)cc1
InChI Key InChIKey=NUWFSHWNAZZTED-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 73920
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke
Curated by ChEMBL
National Institute of Neurological Disorders and Stroke
Curated by ChEMBL
Affinity DataEC50: 710nMAssay Description:Agonist activity at human D3R expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by beta-galactosidas...More data for this Ligand-Target Pair
Affinity DataEC50: 710nMAssay Description:Compounds were tested for their ability to compete with the orthosteric radioligand [3H]methylspiperone for binding to the D3 DAR using stable HEK ce...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke
Curated by ChEMBL
National Institute of Neurological Disorders and Stroke
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]-methylspiperon from human D3R expressed in HEK293 cell membranes measured after 90 mins in EBSS buffer by topcount assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+4nMAssay Description:For a secondary-screen and selectivity assays, DAR PathHunter βarrestin GPCR cell lines from DiscoverX (Fremont, Calif.) were used. In the D2 Re...More data for this Ligand-Target Pair
Affinity DataIC50: 1.57E+4nMAssay Description:Antagonist activity at human D2R expressed in CHOK1 cells assessed as inhibition of dopamine-induced beta-arrestin recruitment measured after 120 min...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:For a secondary-screen and selectivity assays, DAR PathHunter βarrestin GPCR cell lines from DiscoverX (Fremont, Calif.) were used. In the D2 Re...More data for this Ligand-Target Pair
Affinity DataEC50: >7.50E+4nMAssay Description:Primary Collaborators: Kenneth Kaye,Brigham & Womens,Boston MA,kkaye@rics.bwh.harvard.edu,617-525-4256 Chantal Beauchemin,Brigham & Womens,Boston MA,...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [3H]-methylspiperon from human D2RL expressed in HEK293 cell membranes measured after 90 mins by topcount assayMore data for this Ligand-Target Pair