BDBM739680 1-((R)-3-((5-((1R,2R)-2-(methoxymethyl)cyclopropyl)- 7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1- yl)prop-2-en-1-one::US12297203, Example 26

SMILES C=CC(=O)N1CCC[C@@H](Nc2ncnc3[nH]cc(C4C[C@H]4COC)c23)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 739680   

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandPNGBDBM739680(1-((R)-3-((5-((1R,2R)-2-(methoxymethyl)cyclopropyl...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent