BDBM739740 (S)-1-(3-(4-amino-3-((6-fluoro-1-(methyl-d3)-1Hbenzo[d]imidazol-5-yl)ethynyl)-7-(thiazol-2-yl)-1Hpyrazolo[4,3-c]pyridin-1-yl)pyrrolidin-1-yl)prop-2-en-1-one::US20250152564, Example 25

SMILES [2H]C([2H])([2H])n6cnc5cc(C#Cc3nn([C@H]1CCN(C(=O)C=C)C1)c4c(c2nccs2)cnc(N)c34)c(F)cc56

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 739740   

LigandPNGBDBM739740((S)-1-(3-(4-amino-3-((6-fluoro-1-(methyl-d3)-1Hben...)
Affinity DataIC50: 0.600nMAssay Description:TR-FRET (time-resolved fluorescence resonance energy transfer) method was used to detect the inhibitory activity of the compounds on FGFR1, FGFR2, FG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM739740((S)-1-(3-(4-amino-3-((6-fluoro-1-(methyl-d3)-1Hben...)
Affinity DataIC50: 1.5nMAssay Description:TR-FRET (time-resolved fluorescence resonance energy transfer) method was used to detect the inhibitory activity of the compounds on FGFR1, FGFR2, FG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM739740((S)-1-(3-(4-amino-3-((6-fluoro-1-(methyl-d3)-1Hben...)
Affinity DataIC50: 5.70nMAssay Description:TR-FRET (time-resolved fluorescence resonance energy transfer) method was used to detect the inhibitory activity of the compounds on FGFR1, FGFR2, FG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent