BDBM739751 (S)-1-(3-(7-acetyl-4-amino-3-((1-cyclopropyl-6-fluoro-2-methyl-1H-benzo[d]imidazol-5-yl)ethynyl)-1H-pyrazolo[4,3-c]pyridin-1-yl)pyrrolidin-1-yl)prop-2-en-1-one::US20250152564, Example 55

SMILES C=CC(=O)N1CC[C@H](n2nc(C#Cc3cc4nc(C)n(C5CC5)c4cc3F)c3c(N)ncc(C(C)=O)c32)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 739751   

LigandPNGBDBM739751((S)-1-(3-(7-acetyl-4-amino-3-((1-cyclopropyl-6-flu...)
Affinity DataIC50: 1nMAssay Description:TR-FRET (time-resolved fluorescence resonance energy transfer) method was used to detect the inhibitory activity of the compounds on FGFR1, FGFR2, FG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM739751((S)-1-(3-(7-acetyl-4-amino-3-((1-cyclopropyl-6-flu...)
Affinity DataIC50: 2.80nMAssay Description:TR-FRET (time-resolved fluorescence resonance energy transfer) method was used to detect the inhibitory activity of the compounds on FGFR1, FGFR2, FG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM739751((S)-1-(3-(7-acetyl-4-amino-3-((1-cyclopropyl-6-flu...)
Affinity DataIC50: 4.40nMAssay Description:TR-FRET (time-resolved fluorescence resonance energy transfer) method was used to detect the inhibitory activity of the compounds on FGFR1, FGFR2, FG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent