BDBM739804 (1R,2S,5S)—N-((1S)-1-Cyano-2-(2-carbonylindolin-3-yl)ethyl)-3-((S)-2-((1r,3R,5R,7S)-3-hydroxyadamantan-1-yl)-2-(2,2,2-trifluoroacetamido)acetyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide ::US20250154131, Compound 5

SMILES CC1(C)[C@@H]2[C@@H](C(=O)N[C@H](C#N)CC3C(=O)Nc4ccccc43)N(C(=O)[C@@H](NC(=O)C(F)(F)F)C34CC5CC(CC(O)(C5)C3)C4)C[C@@H]21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 739804   

TargetReplicase polyprotein 1ab(2019-nCoV)
Hainan Simcere Pharmaceutical

US Patent
LigandPNGBDBM739804((1R,2S,5S)—N-((1S)-1-Cyano-2-(2-carbonylindolin-3-...)
Affinity DataIC50: 69.8nMAssay Description:200 nL of 3-fold serially diluted compound (final concentration: 10 μM-0.5 nM) was incubated with 10 μL of 200 nM recombinant 3CL protease (BPS Kit) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent