BDBM740176 N-((1S)-1-cyclohexyl- 2-((2-((2- fluorobenzyl)carbamoyl)- 2-(6-oxo-5,7- diazaspiro[2.5]octan-5- yl)-2,3-dihydro-1H- inden-5-yl)amino)-2- oxoethyl)-1-methyl-1H- pyrazole-5-carboxamide::US20250154138, Example 175

SMILES Cn1nccc1C(=O)N[C@H](C(=O)Nc1ccc2c(c1)CC(C(=O)Nc1cccc(F)c1)(N1CC3(CC3)CNC1=O)C2)C1CCCCC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 740176   

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandPNGBDBM740176(N-((1S)-1-cyclohexyl- 2-((2-((2- fluorobenzyl)carb...)
Affinity DataIC50: 22.4nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent