BDBM740791 cis-N-(2-chloro-3- ((3,5-dimethyl-4-oxo- 3,4- dihydroquinazolin-6- yl)amino)-4,5- difluorophenyl)-3,4- difluoropyrrolidine-1- sulfonamide::US12303509, Example 95

SMILES Cc1c(Nc2c(F)c(F)cc(NS(=O)(=O)N3C[C@@H](F)[C@@H](F)C3)c2Cl)ccc2ncn(C)c(=O)c12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 740791   

LigandPNGBDBM740791(cis-N-(2-chloro-3- ((3,5-dimethyl-4-oxo- 3,4- dihy...)
Affinity DataIC50: 2nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged “tracer” bound to B-Raf via TR-FRET from...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent