BDBM741059 S-(2-((5-((6-carbamoyl-4-(3-chloro-4-(3-cyclopropylurea)phenoxy)quinolin-7-yl)oxy)pentyl)amino)-2-oxo-ethyl)thioacetate::US12304898, Example 69

SMILES CC(=O)SCC(=O)NCCCCCOc1cc2nccc(Oc3ccc(NC(=O)NC4CC4)c(Cl)c3)c2cc1C(N)=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 741059   

TargetVascular endothelial growth factor receptor 2(Human)
Primegene (Beijing)

US Patent
LigandPNGBDBM741059(S-(2-((5-((6-carbamoyl-4-(3-chloro-4-(3-cyclopropy...)
Affinity DataIC50: 0.960nMAssay Description:Detect compounds on VEGFR2 (KDR) by mobility shift assay. The initial test concentration of a compound was 1000 nM, 3 times dilution, 10 concentratio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Primegene (Beijing)

US Patent
LigandPNGBDBM741059(S-(2-((5-((6-carbamoyl-4-(3-chloro-4-(3-cyclopropy...)
Affinity DataIC50: 8.94nMAssay Description:Prepare a 10 mM stock solution of a compound with DMSO. Take 10 μl of stock solution and dilute with 90 μl DMSO to become a 1 mM working solution. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent