BDBM741236 US20250161307, Example 79

SMILES COc1ccc(-c2cc(-c3ccccc3)nc3cc(C(=O)NCCCn4ccnc4)nn23)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 741236   

TargetSpermine oxidase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM741236(US20250161307, Example 79)
Affinity DataIC50: 2.42E+5nMAssay Description:Test compounds (75 nL) dissolved in DMSO were added to a 384-well white assay plate (Greiner Bio-one, catalog #784075) using an ECHO Acoustic Dispens...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetPeroxisomal N(1)-acetyl-spermine/spermidine oxidase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM741236(US20250161307, Example 79)
Affinity DataIC50: 9.14E+5nMAssay Description:The hPAOX assay was run and the data analyzed similarly to the hSMOX assay described above, except the reactions contained 60 pM recombinant PAOX wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent