BDBM741626 N-hydroxy-4-(3-(4-((((1R,2S)-2-(1,3,3-trimethyl-2-oxoindolin-5-yl)cyclopropyl)amino)methyl)piperidin-1-yl)propyl)benzamide::US20250162994, Example 9

SMILES CN1C(=O)C(C)(C)c2cc([C@@H]3C[C@H]3NCC3CCN(CCCc4ccc(C(=O)NO)cc4)CC3)ccc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 741626   

TargetHistone deacetylase 6(Human)TBA
LigandPNGBDBM741626(N-hydroxy-4-(3-(4-((((1R,2S)-2-(1,3,3-trimethyl-2-...)
Affinity DataIC50: 192nMAssay Description:Histone deacetylase assay was done as per manufacturer's instructions. Briefly, assay buffer, 200 uM HDAC substrate (fluorogenic HDAC acetylated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM741626(N-hydroxy-4-(3-(4-((((1R,2S)-2-(1,3,3-trimethyl-2-...)
Affinity DataIC50: 403nMAssay Description:LSD1 enzyme was produced in house. Tranylcypromine (TCP), LSD1 inhibitor was procured from Selleckchem. LSD1 enzyme, TCP and Biotinylated peptide sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent