BDBM741632 N-(2-aminophenyl)-4-(3-(4-((((1R,2S)-2-(4-fluorophenyl)cyclopropyl)amino)methyl)piperidin-1-yl)propyl)benzamide::US20250162994, Example 15

SMILES Nc1ccccc1NC(=O)c1ccc(CCCN2CCC(CN[C@@H]3C[C@H]3c3ccc(F)cc3)CC2)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 741632   

TargetLysine-specific histone demethylase 1A(Human)
Jubilant Epicore

US Patent
LigandPNGBDBM741632(N-(2-aminophenyl)-4-(3-(4-((((1R,2S)-2-(4-fluoroph...)
Affinity DataIC50: 9nMAssay Description:LSD1 enzyme was produced in house. Tranylcypromine (TCP), LSD1 inhibitor was procured from Selleckchem. LSD1 enzyme, TCP and Biotinylated peptide sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Jubilant Epicore

US Patent
LigandPNGBDBM741632(N-(2-aminophenyl)-4-(3-(4-((((1R,2S)-2-(4-fluoroph...)
Affinity DataIC50: 7.72E+3nMAssay Description:Histone deacetylase assay was done as per manufacturer's instructions. Briefly, assay buffer, 200 uM HDAC substrate (fluorogenic HDAC acetylated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent