BDBM743436 US9750744, Example 45 isomer 2

SMILES O=C3NC[C@H](O)COc1ccc(F)cc1[C@@H]2CC(F)(F)CN2c5ccn4ncc3c4n5

InChI Key InChIKey=RQZIXOOARXBNHW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 743436   

TargetHigh affinity nerve growth factor receptor(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 743436BDBM743436(US9750744, Example 45 isomer 2)
Affinity DataIC50: 55nMAssay Description:The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen Eu Kinase Binding Assay. In this assay, His-tagged recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/11/2019
Entry Details
US Patent