BDBM743458 US20250163072, Example RM351
SMILES CC(C)[C@@H](C(=O)N[C@H]1Cc2cc(O)cc(c2)-c2ccc3c(C(C)(C)C#N)cn(c3c2)CC(C)(C)COC(=O)[C@@H]2CCCN(N2)C1=O)N1CCCC2(CCN(C(=O)CCl)C2)C1=O
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 743458
Affinity DataIC50: 1.79E+3nMAssay Description:HEK293 cells were grown and maintained using DMEM medium (Thermo Fisher Scientific) with 10% fetal bovine serum and 1% penicillin/streptomycin. Both ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:In this example, TR-FRET was also used to measure the compound or compound-CYPA dependent disruption of the KRAS G12C-BRAF complex. This protocol was...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:In this example, TR-FRET was also used to measure the compound or compound-CYPA dependent disruption of the KRAS G12C-BRAF complex. This protocol was...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:In this example, TR-FRET was also used to measure the compound or compound-CYPA dependent disruption of the KRAS G12C-BRAF complex. This protocol was...More data for this Ligand-Target Pair