BDBM743472 N-((S)-1-(((S)-4-(4-methylbenzylmethylamino)-3, 4-dione-1-((S)-2-oxopiperidin-3-yl)but-2-yl) amino)-3-cyclohexyl-1-oxopropan-2-yl)- benzofuran-2-carboxamide::US12636275, Compound A272

SMILES Cc1ccc(CN(C)C(=O)C(=O)[C@H](C[C@@H]2CCCNC2=O)NC(=O)[C@H](CC2CCCCC2)NC(=O)c2cc3ccccc3o2)cc1

InChI Key InChIKey=GVGBHPQXESEMQH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 743472   

TargetReplicase polyprotein 1a(2019-nCoV)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 743472BDBM743472(N-((S)-1-(((S)-4-(4-methylbenzylmethylamino)-3, 4-...)
Affinity DataIC50: 4.80E+3nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent