BDBM743540 US20250163074, Example 66

SMILES CCN1CC2(C1)CN(c1ccc(Nc3ncc(F)c(-c4ccc5c(c4)C4(CCCC4)CN(C)C5=O)n3)nc1)C2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 743540   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM743540(US20250163074, Example 66)
Affinity DataIC50: 20nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM743540(US20250163074, Example 66)
Affinity DataIC50: 110nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK6/Cyc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2025
Entry Details
US Patent