BDBM743610 US20250163077, Example 36

SMILES Cc1ccc(O)c(C)c1-n1c(N)c(C(=O)N2CCn3nccc3C2)c2ncc(C(F)(F)F)nc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 743610   

LigandPNGBDBM743610(US20250163077, Example 36)
Affinity DataIC50: 275nMAssay Description:Compound serial dilution is performed by Echo, and the final concentrations vary from 10 μM to 0.5 nM. This was filled by the addition of 5 μL/well o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2025
Entry Details
US Patent

TargetMyelin transcription factor 1(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandPNGBDBM743610(US20250163077, Example 36)
Affinity DataIC50: 359nMAssay Description:Inhibition of human recombinant MYT1 incubated for 60 mins in presence of tracer178 by HTRF analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetWee1-like protein kinase(Human)
Insilico Medicine IP

US Patent
LigandPNGBDBM743610(US20250163077, Example 36)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound serial dilution is performed by Echo, and the final concentrations vary from 10 μM to 0.5 nM. This was filled by the addition of 5 μL/well o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2025
Entry Details
US Patent

TargetWee1-like protein kinase(Human)
Insilico Medicine IP

US Patent
LigandPNGBDBM743610(US20250163077, Example 36)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant Wee1 preincubated with compound for for 15 mins followed by ATP addition and measured after 60 mins by ADP Glo lumine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed