BDBM743642 2-((6-((5-chloro-2-(4-(2- (2-(2-(3-((2-(2,6- dioxopiperidin-3-yl)-1- oxoisoindolin-5- yl)oxy)propoxy)ethoxy) ethoxy)ethoxy)piperidin- 1-yl)pyrimidin-4- yl)amino)-1-methyl-2- oxo-1,2-dihydroquinolin- 3-yl)oxy)-N- methylacetamide::US12310975, Example 168

SMILES CNC(=O)COc1cc2cc(Nc3nc(N4CCC(OCCOCCOCCOCCCOc5ccc6c(c5)CN(C5CCC(=O)NC5=O)C6=O)CC4)ncc3Cl)ccc2n(C)c1=O

InChI Key InChIKey=VRRVPJQZMQARNW-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 743642   

TargetB-cell lymphoma 6 protein(Human)
Arvinas

US Patent
LigandChemical structure of BindingDB Monomer ID 743642BDBM743642(2-((6-((5-chloro-2-(4-(2- (2-(2-(3-((2-(2,6- dioxo...)
Affinity DataIC50: 30nMAssay Description:Assay buffer A: 50 mM HEPES pH 7.5, 125 mM NaCl, 0.01% TritonX.Assay buffer B (made fresh): buffer A+1 mM Glutathione (or 0.5 mM DTT).Assay buffer C ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2025
Entry Details
US Patent