BDBM743696 2-((6-((5-chloro-2-(3- (((2-(2,6-dioxopiperidin- 3-yl)-1,3-dioxoisoindolin- 4-yl)oxy)methyl)-4- methylpiperazin-1- yl)pyrimidin-4- yl)amino)-1-methyl-2- oxo-1,2-dihydroquinolin- 3-yl)oxy)-N- methylacetamide::US12310975, Example 231

SMILES CNC(=O)COc1cc2cc(Nc3nc(N4CCN(C)C(COc5cccc6c5C(=O)N(C5CCC(=O)NC5=O)C6=O)C4)ncc3Cl)ccc2n(C)c1=O

InChI Key InChIKey=UVJBNGFFMZIIJK-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 743696   

TargetB-cell lymphoma 6 protein(Human)
Arvinas

US Patent
LigandChemical structure of BindingDB Monomer ID 743696BDBM743696(2-((6-((5-chloro-2-(3- (((2-(2,6-dioxopiperidin- 3...)
Affinity DataIC50: 100nMAssay Description:Assay buffer A: 50 mM HEPES pH 7.5, 125 mM NaCl, 0.01% TritonX.Assay buffer B (made fresh): buffer A+1 mM Glutathione (or 0.5 mM DTT).Assay buffer C ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2025
Entry Details
US Patent