BDBM743735 7-({5-chloro-2-[4-(2-{1- [2-(2,6-dioxopiperidin-3- yl)-1,3-dioxo-2,3- dihydro-1H-isoindol-5- yl]piperidin-4-yl}propan- 2-yl)piperazin-1- yl]pyrimidin-4- yl}amino)-N,4-dimethyl- 3-oxo-3,4-dihydro-2H- 1,4-benzoxazine-2- carboxamide::US12310975, Example 274

SMILES CNC(=O)C1Oc2cc(Nc3nc(N4CCN(C(C)(C)C5CCN(c6ccc7c(c6)C(=O)N(C6CCC(=O)NC6=O)C7=O)CC5)CC4)ncc3Cl)ccc2N(C)C1=O

InChI Key InChIKey=DVSXOIZZNUTYLX-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 743735   

TargetB-cell lymphoma 6 protein(Human)
Arvinas

US Patent
LigandChemical structure of BindingDB Monomer ID 743735BDBM743735(7-({5-chloro-2-[4-(2-{1- [2-(2,6-dioxopiperidin-3-...)
Affinity DataIC50: 100nMAssay Description:Assay buffer A: 50 mM HEPES pH 7.5, 125 mM NaCl, 0.01% TritonX.Assay buffer B (made fresh): buffer A+1 mM Glutathione (or 0.5 mM DTT).Assay buffer C ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2025
Entry Details
US Patent