BDBM743740 2-{[6-({5-chloro-2-[4-(1- {4-[2-(2,6- dioxopiperidin-3-yl)-1,3- dioxo-2,3-dihydro-1H- isoindol-5-yl]piperazin-1- yl}-2-methylpropan-2- yl)piperazin-1- yl]pyrimidin-4- yl}amino)-1-methyl-2- oxo-1,2-dihydroquinolin- 3-yl]oxy}-N- methylacetamide::US12310975, Example 279

SMILES CNC(=O)COc1cc2cc(Nc3nc(N4CCN(C(C)(C)CN5CCN(c6ccc7c(c6)C(=O)N(C6CCC(=O)NC6=O)C7=O)CC5)CC4)ncc3Cl)ccc2n(C)c1=O

InChI Key InChIKey=MVWVUOBVAAISNY-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 743740   

TargetB-cell lymphoma 6 protein(Human)
Arvinas

US Patent
LigandChemical structure of BindingDB Monomer ID 743740BDBM743740(2-{[6-({5-chloro-2-[4-(1- {4-[2-(2,6- dioxopiperid...)
Affinity DataIC50: 30nMAssay Description:Assay buffer A: 50 mM HEPES pH 7.5, 125 mM NaCl, 0.01% TritonX.Assay buffer B (made fresh): buffer A+1 mM Glutathione (or 0.5 mM DTT).Assay buffer C ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2025
Entry Details
US Patent