BDBM743746 5-(4-{2-[4-(5-chloro-4- {[1-methyl-3-(5-methyl- 1,3,4-oxadiazol-2-yl)-2- oxo-1,2-dihydroquinolin- 6-yl]amino}pyrimidin-2- yl)piperazin-1-yl]propan- 2-yl}piperidin-1-yl)-2- (2,6-dioxopiperidin-3-yl)- 2,3-dihydro-1H- isoindole-1,3-dione::US12310975, Example 285

SMILES Cc1nnc(-c2cc3cc(Nc4nc(N5CCN(C(C)(C)C6CCN(c7ccc8c(c7)C(=O)N(C7CCC(=O)NC7=O)C8=O)CC6)CC5)ncc4Cl)ccc3n(C)c2=O)o1

InChI Key InChIKey=ZSDKMILDBPWLQT-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 743746   

TargetB-cell lymphoma 6 protein(Human)
Arvinas

US Patent
LigandChemical structure of BindingDB Monomer ID 743746BDBM743746(5-(4-{2-[4-(5-chloro-4- {[1-methyl-3-(5-methyl- 1,...)
Affinity DataIC50: 30nMAssay Description:Assay buffer A: 50 mM HEPES pH 7.5, 125 mM NaCl, 0.01% TritonX.Assay buffer B (made fresh): buffer A+1 mM Glutathione (or 0.5 mM DTT).Assay buffer C ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2025
Entry Details
US Patent