BDBM743762 2-{[6-({5-chloro-2-[4- ({1''-[2-(2,6- dioxopiperidin-3-yl)-1,3- dioxo-2,3-dihydro-1H- isoindol-5-yl]-[1,3''- biazetidin]-3- yl}methyl)piperazin-1- yl]pyrimidin-4-::US12310975, Example 302

SMILES CCn1c(=O)c(OCC(=O)NC)cc2cc(Nc3nc(N4CCN(CC5CN(C6CN(c7ccc8c(c7)C(=O)N(C7CCC(=O)NC7=O)C8=O)C6)C5)CC4)ncc3Cl)ccc21

InChI Key InChIKey=CHJMUNRSCBWUDI-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 743762   

TargetB-cell lymphoma 6 protein(Human)
Arvinas

US Patent
LigandChemical structure of BindingDB Monomer ID 743762BDBM743762(2-{[6-({5-chloro-2-[4- ({1'-[2-(2,6- dioxopiperidi...)
Affinity DataIC50: 30nMAssay Description:Assay buffer A: 50 mM HEPES pH 7.5, 125 mM NaCl, 0.01% TritonX.Assay buffer B (made fresh): buffer A+1 mM Glutathione (or 0.5 mM DTT).Assay buffer C ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2025
Entry Details
US Patent