BDBM743828 rac-3-[(3R,5S)-4-({1-[5- chloro-4-({1-methyl-3- [(methylcarbamoyl) methoxy]-2-oxo-1,2- dihydroquinolin-6- yl}amino)pyrimidin-2- yl]piperidin-4- yl}methyl)-3,5- dimethylpiperazin-1-yl]- N-(2,6-dioxopiperidin-3- yl)-2-fluorobenzamide::US12310975, Example 370

SMILES CNC(=O)COc1cc2cc(Nc3nc(N4CCC(CN5[C@H](C)CN(c6cccc(C(=O)NC7CCC(=O)NC7=O)c6F)C[C@@H]5C)CC4)ncc3Cl)ccc2n(C)c1=O

InChI Key InChIKey=DMWYTIZFYLGKKO-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 743828   

TargetB-cell lymphoma 6 protein(Human)
Arvinas

US Patent
LigandChemical structure of BindingDB Monomer ID 743828BDBM743828(rac-3-[(3R,5S)-4-({1-[5- chloro-4-({1-methyl-3- [(...)
Affinity DataIC50: 30nMAssay Description:Assay buffer A: 50 mM HEPES pH 7.5, 125 mM NaCl, 0.01% TritonX.Assay buffer B (made fresh): buffer A+1 mM Glutathione (or 0.5 mM DTT).Assay buffer C ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2025
Entry Details
US Patent