BDBM743879 2-{[6-({5-chloro-2-[4- ({2-[2-(2,6- dioxopiperidin-3-yl)-1- oxo-2,3-dihydro-1H- isoindol-4-yl]-2- azaspiro[3.3]heptan-6- yl}oxy)piperidin-1- yl]pyrimidin-4- yl}amino)-2-oxo-1- (propan-2-yl)-1,2- dihydroquinolin-3- yl]oxy}-N- methylacetamide::US12310975, Example 424

SMILES CNC(=O)COc1cc2cc(Nc3nc(N4CCC(OC5CC6(C5)CN(c5cccc7c5CN(C5CCC(=O)NC5=O)C7=O)C6)CC4)ncc3Cl)ccc2n(C(C)C)c1=O

InChI Key InChIKey=XBZAJXDJHRXLRW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 743879   

TargetB-cell lymphoma 6 protein(Human)
Arvinas

US Patent
LigandChemical structure of BindingDB Monomer ID 743879BDBM743879(2-{[6-({5-chloro-2-[4- ({2-[2-(2,6- dioxopiperidin...)
Affinity DataIC50: 30nMAssay Description:Assay buffer A: 50 mM HEPES pH 7.5, 125 mM NaCl, 0.01% TritonX.Assay buffer B (made fresh): buffer A+1 mM Glutathione (or 0.5 mM DTT).Assay buffer C ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2025
Entry Details
US Patent