BDBM743884 4-[6-({1-[5-chloro-4-({3- [(methylcarbamoyl) methoxy]- 2-oxo-1-(propan-2- yl)-1,2-dihydroquinolin- 6-yl}amino)pyrimidin-2- yl]piperidin-4-yl}oxy)-2- azaspiro[3.3]heptan-2- yl]-N-(2,6- dioxopiperidin-3-yl)-2- methoxybenzamide::US12310975, Example 429

SMILES CNC(=O)COc1cc2cc(Nc3nc(N4CCC(OC5CC6(C5)CN(c5ccc(C(=O)NC7CCC(=O)NC7=O)c(OC)c5)C6)CC4)ncc3Cl)ccc2n(C(C)C)c1=O

InChI Key InChIKey=ZHDJDWBISVXAMU-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 743884   

TargetB-cell lymphoma 6 protein(Human)
Arvinas

US Patent
LigandChemical structure of BindingDB Monomer ID 743884BDBM743884(4-[6-({1-[5-chloro-4-({3- [(methylcarbamoyl) metho...)
Affinity DataIC50: 10nMAssay Description:Assay buffer A: 50 mM HEPES pH 7.5, 125 mM NaCl, 0.01% TritonX.Assay buffer B (made fresh): buffer A+1 mM Glutathione (or 0.5 mM DTT).Assay buffer C ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2025
Entry Details
US Patent