BDBM743921 3-[1-({1-[5-chloro-4-({1- methyl-3- [(methylcarbamoyl) methoxy]-2-oxo-1,2- dihydroquinolin-6- yl}amino)pyrimidin-2- yl]piperidin-4- yl}methyl)piperidin-4- yl]-N-(2,6- dioxopiperidin-3-yl)-2- fluoro-5- methoxybenzamide::US12310975, Example 467

SMILES CNC(=O)COc1cc2cc(Nc3nc(N4CCC(CN5CCC(c6cc(OC)cc(C(=O)NC7CCC(=O)NC7=O)c6F)CC5)CC4)ncc3Cl)ccc2n(C)c1=O

InChI Key InChIKey=PHCKRFMMMKYXBW-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 743921   

TargetB-cell lymphoma 6 protein(Human)
Arvinas

US Patent
LigandChemical structure of BindingDB Monomer ID 743921BDBM743921(3-[1-({1-[5-chloro-4-({1- methyl-3- [(methylcarbam...)
Affinity DataIC50: 30nMAssay Description:Assay buffer A: 50 mM HEPES pH 7.5, 125 mM NaCl, 0.01% TritonX.Assay buffer B (made fresh): buffer A+1 mM Glutathione (or 0.5 mM DTT).Assay buffer C ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2025
Entry Details
US Patent