BDBM743924 2-[(6-{[5-chloro-2- (dimethylamino) pyrimidin- 4-yl]amino}-1-(2-{[2- (2,6-dioxopiperidin-3-yl)- 1,3-dioxo-2,3-dihydro- 1H-isoindol-5- yl]oxy}ethyl)-2-oxo-1,2- dihydroquinolin-3- yl)oxy]-N- methylacetamide::US12310975, Example 470

SMILES CNC(=O)COc1cc2cc(Nc3nc(N(C)C)ncc3Cl)ccc2n(CCOc2ccc3c(c2)C(=O)N(C2CCC(=O)NC2=O)C3=O)c1=O

InChI Key InChIKey=VAZUTXMDDPHYRY-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 743924   

TargetB-cell lymphoma 6 protein(Human)
Arvinas

US Patent
LigandChemical structure of BindingDB Monomer ID 743924BDBM743924(2-[(6-{[5-chloro-2- (dimethylamino) pyrimidin- 4-y...)
Affinity DataIC50: 30nMAssay Description:Assay buffer A: 50 mM HEPES pH 7.5, 125 mM NaCl, 0.01% TritonX.Assay buffer B (made fresh): buffer A+1 mM Glutathione (or 0.5 mM DTT).Assay buffer C ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2025
Entry Details
US Patent