BDBM743958 4-(4-{[4-(5-chloro-4-{[3- (3-hydroxy-3- methylbutyl)-1-methyl-2- oxo-2,3-dihydro-1H-1,3- benzodiazol-5- yl]amino}pyrimidin-2- yl)piperazin-1- yl]methyl}piperidin-1- yl)-2-(2,6-dioxopiperidin- 3-yl)-2,3-dihydro-1H- isoindole-1,3-dione::US12310975, Example 505

SMILES Cn1c(=O)n(CCC(C)(C)O)c2cc(Nc3nc(N4CCN(CC5CCN(c6cccc7c6C(=O)N(C6CCC(=O)NC6=O)C7=O)CC5)CC4)ncc3Cl)ccc21

InChI Key InChIKey=NRVUFSVJPWTSJR-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 743958   

TargetB-cell lymphoma 6 protein(Human)
Arvinas

US Patent
LigandChemical structure of BindingDB Monomer ID 743958BDBM743958(4-(4-{[4-(5-chloro-4-{[3- (3-hydroxy-3- methylbuty...)
Affinity DataIC50: 75nMAssay Description:Assay buffer A: 50 mM HEPES pH 7.5, 125 mM NaCl, 0.01% TritonX.Assay buffer B (made fresh): buffer A+1 mM Glutathione (or 0.5 mM DTT).Assay buffer C ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2025
Entry Details
US Patent