BDBM744005 1-Isopropyl-N-(5-(4-isopropylpiperazin- 1-yl)pyridin-2-yl)-1H-[1,2,3]triazolo [4,5-h]quinazolin-8-amine hydrochloride::US12312355, Compound I-7

SMILES CC(C)N1CCN(c2ccc(Nc3ncc4ccc5nnn(C(C)C)c5c4n3)nc2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 744005   

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Chengdu Cynogen Bio-Pharmaceutical Technology

US Patent
LigandPNGBDBM744005(1-Isopropyl-N-(5-(4-isopropylpiperazin- 1-yl)pyrid...)
Affinity DataIC50: 10nMAssay Description:The inhibitory effect of the compound on the kinase CDK4/cyclin D3 was tested by the Caliper Mobility Shift Assay method. The final test concentratio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Chengdu Cynogen Bio-Pharmaceutical Technology

US Patent
LigandPNGBDBM744005(1-Isopropyl-N-(5-(4-isopropylpiperazin- 1-yl)pyrid...)
Affinity DataIC50: 10nMAssay Description:The inhibitory effect of the compound on the kinase CDK4/cyclin D3 was tested by the Caliper Mobility Shift Assay method. The final test concentratio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2025
Entry Details
US Patent