BDBM744035 N-(4-((1-Isopropyl-1H-[1,2,3]triazolo[4,5- h]quinazolin-8-yl)amino)phenyl)-N-(2- morpholinoethyl)methanesulfonamide::US12312355, Compound I-37

SMILES CC(C)n1nnc2ccc3cnc(Nc4ccc(N(CCN5CCOCC5)S(C)(=O)=O)cc4)nc3c21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 744035   

LigandPNGBDBM744035(N-(4-((1-Isopropyl-1H-[1,2,3]triazolo[4,5- h]quina...)
Affinity DataIC50: 10nMAssay Description:The inhibitory effect of the compound on the kinase CDK4/cyclin D3 was tested by the Caliper Mobility Shift Assay method. The final test concentratio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM744035(N-(4-((1-Isopropyl-1H-[1,2,3]triazolo[4,5- h]quina...)
Affinity DataIC50: 10nMAssay Description:The inhibitory effect of the compound on the kinase CDK4/cyclin D3 was tested by the Caliper Mobility Shift Assay method. The final test concentratio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM744035(N-(4-((1-Isopropyl-1H-[1,2,3]triazolo[4,5- h]quina...)
Affinity DataIC50: 10nMAssay Description:The inhibitory effect of the compound on the kinase CDK4/cyclin D3 was tested by the Caliper Mobility Shift Assay method. The final test concentratio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent