BDBM745195 7-methoxy-2-[2-(7- methylimidazo[1,2-alpyridin-6- yl)cyclopropyl][1,2,4] triazolo[1,5-c] quinazolin-5-amine::US20250171447, Ex-7

SMILES COc1cccc2c1nc(N)n1nc(C3CC3c3cn4ccnc4cc3C)nc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 745195   

TargetAdenosine receptor A2a(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745195(7-methoxy-2-[2-(7- methylimidazo[1,2-alpyridin-6- ...)
Affinity DataIC50: 1.30nMAssay Description:Binding affinity using SPA was conducted as follows. Test compounds (50 μL) were dispensed into individual wells of a 384-well OptiPlate™ well (Perki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745195(7-methoxy-2-[2-(7- methylimidazo[1,2-alpyridin-6- ...)
Affinity DataIC50: 66.1nMAssay Description:To perform the assay, compounds of the invention to be tested were first solubilized in 100% DMSO and further diluted in 100% DMSO to generate, typic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
US Patent