BDBM745255 US20250171447, Ex-68

SMILES COc1cccc2c1nc(N)n1nc([C@H]3C[C@H](c4ccc(C(C)(C)N)cn4)C3)nc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 745255   

TargetAdenosine receptor A2a(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745255(US20250171447, Ex-68)
Affinity DataIC50: 2nMAssay Description:Binding affinity using SPA was conducted as follows. Test compounds (50 μL) were dispensed into individual wells of a 384-well OptiPlate™ well (Perki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745255(US20250171447, Ex-68)
Affinity DataIC50: 2.20nMAssay Description:To perform the assay, compounds of the invention to be tested were first solubilized in 100% DMSO and further diluted in 100% DMSO to generate, typic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
US Patent