BDBM745256 2-{3-[5-(2- aminopropan-2- yl)pyridin-2- yl]cyclobutyl}- 9-fluoro-7- methoxy [1,2,4] triazolo[1,5-c] quinazolin-5-amine::US20250171447, Ex-69

SMILES COc1cc(F)cc2c1nc(N)n1nc(C3CC(c4ccc(C(C)(C)N)cn4)C3)nc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 745256   

TargetAdenosine receptor A2b(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745256(2-{3-[5-(2- aminopropan-2- yl)pyridin-2- yl]cyclob...)
Affinity DataIC50: 0.300nMAssay Description:To perform the assay, compounds of the invention to be tested were first solubilized in 100% DMSO and further diluted in 100% DMSO to generate, typic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745256(2-{3-[5-(2- aminopropan-2- yl)pyridin-2- yl]cyclob...)
Affinity DataIC50: 6.20nMAssay Description:Binding affinity using SPA was conducted as follows. Test compounds (50 μL) were dispensed into individual wells of a 384-well OptiPlate™ well (Perki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
US Patent