BDBM745284 7-methoxy-2- (cis-3-{4- [(piperazin-1- yl)methyl]phenyl} cyclobutyl)[1,2, 4]triazolo[1,5- c]quinazolin-5- amine::US20250171447, Ex-97

SMILES Cc1cccc2c1nc(N)n1nc([C@H]3C[C@@H](c4ccc(CN5CCNCC5)cc4)C3)nc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 745284   

TargetAdenosine receptor A2a(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745284(7-methoxy-2- (cis-3-{4- [(piperazin-1- yl)methyl]p...)
Affinity DataIC50: 0.300nMAssay Description:Binding affinity using SPA was conducted as follows. Test compounds (50 μL) were dispensed into individual wells of a 384-well OptiPlate™ well (Perki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
US Patent