BDBM745463 Synthesis of 2-((4,6-dimethoxypyrimidin-2-yl)amino)-8-fluoroindolo[2,1-b]quinazoline-6,12-dione ::US20250171452, Compound 135

SMILES COc1cc(OC)nc(Nc2ccc3nc4n(c(=O)c3c2)-c2ccc(F)cc2C4=O)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 745463   

TargetIndoleamine 2,3-dioxygenase 2(Human)
Viscient Bio

US Patent
LigandPNGBDBM745463(Synthesis of 2-((4,6-dimethoxypyrimidin-2-yl)amino...)
Affinity DataIC50: 10nMAssay Description:The reference compound INCB024360 (a potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor) and test compounds were diluted from source s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
9/23/2025
Entry Details
US Patent