BDBM746065 5-chloro-1-{1- [trans-3- (methoxymethyl)cyclo- butyl]-1H-pyrazol- 4-yl}-6-[4-(3- methyloxetan-3- yl)piperazin-1-yl]- 1H-indazole::US12319671, Example 5.18

SMILES COC[C@H]1C[C@H](n2cc(-n3ncc4cc(Cl)c(N5CCN(C6(C)COC6)CC5)cc43)cn2)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 746065   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM746065(5-chloro-1-{1- [trans-3- (methoxymethyl)cyclo- but...)
Affinity DataIC50: 625nMAssay Description:Assays were performed in the presence of 134 μM ATP (Km ATP). Upon completion, the assay was stopped, and phosphorylated substrate detected with a te...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/25/2025
Entry Details
US Patent