BDBM746135 (1R,5S)-3-[5-chloro-1-[1-[3- (methoxymethyl)-1- bicyclo[1.1.1]pentanyl] pyrazol-4-yl]indazol-6-yl]-8- methyl-3- azabicyclo[3.2.1]octan-8-ol::US12319671, Example 6.63

SMILES COCC12CC3(n4cc(-n5ncc6cc(Cl)c(N7C[C@H]8CC[C@@H](C7)C8(C)O)cc65)cn4)CC13C2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 746135   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM746135((1R,5S)-3-[5-chloro-1-[1-[3- (methoxymethyl)-1- bi...)
Affinity DataIC50: 625nMAssay Description:Assays were performed in the presence of 134 μM ATP (Km ATP). Upon completion, the assay was stopped, and phosphorylated substrate detected with a te...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/25/2025
Entry Details
US Patent