BDBM746139 (1R,5R,8R)-3-[5-chloro-1-(1- cyclopropylpyrazol-4- yl)indazol-6-yl]-8-methyl-6- oxa-3-azabicyclo[3.2.1]octan- 8-ol::US12319671, Example 6.67

SMILES C[C@@]1(O)[C@H]2CO[C@@H]1CN(c1cc3c(cnn3-c3cnn(C4CC4)c3)cc1Cl)C2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 746139   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM746139((1R,5R,8R)-3-[5-chloro-1-(1- cyclopropylpyrazol-4-...)
Affinity DataIC50: 390nMAssay Description:Assays were performed in the presence of 134 μM ATP (Km ATP). Upon completion, the assay was stopped, and phosphorylated substrate detected with a te...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/25/2025
Entry Details
US Patent