BDBM746145 (1R,5S)-3-[5-chloro-1-(1- cyclopropylpyrazol-4-yl)indazol-6- yl]-8-(6-methyl-3-pyridyl)-3- azabicyclo[3.2.1]octan-8-ol::US12319671, Example 6.73

SMILES Cc1ccc(C2(O)[C@@H]3CC[C@H]2CN(c2cc4c(cnn4-c4cnn(C5CC5)c4)cc2Cl)C3)cn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 746145   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM746145((1R,5S)-3-[5-chloro-1-(1- cyclopropylpyrazol-4-yl)...)
Affinity DataIC50: 248nMAssay Description:Assays were performed in the presence of 134 μM ATP (Km ATP). Upon completion, the assay was stopped, and phosphorylated substrate detected with a te...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/25/2025
Entry Details
US Patent