BDBM746148 (1R,5S)-3-[5-chloro-1-(1- methylpyrazol-4-yl)indazol-6-yl]- 8-(2,6-dimethyl-3-pyridyl)-3- azabicyclo[3.2.1]octan-8-ol::US12319671, Example 6.76

SMILES Cc1ccc(C2(O)[C@@H]3CC[C@H]2CN(c2cc4c(cnn4-c4cnn(C)c4)cc2Cl)C3)c(C)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 746148   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM746148((1R,5S)-3-[5-chloro-1-(1- methylpyrazol-4-yl)indaz...)
Affinity DataIC50: 625nMAssay Description:Assays were performed in the presence of 134 μM ATP (Km ATP). Upon completion, the assay was stopped, and phosphorylated substrate detected with a te...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/25/2025
Entry Details
US Patent