BDBM746152 (1S,5R)-3-[5-chloro-1-(1- methylpyrazol-4-yl)indazol-6-yl]- 8-(3-pyridyl)-3- azabicyclo[3.2.1]octan-8-ol::US12319671, Example 6.80

SMILES Cn1cc(-n2ncc3cc(Cl)c(N4C[C@H]5CC[C@@H](C4)C5(O)c4cccnc4)cc32)cn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 746152   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM746152((1S,5R)-3-[5-chloro-1-(1- methylpyrazol-4-yl)indaz...)
Affinity DataIC50: 625nMAssay Description:Assays were performed in the presence of 134 μM ATP (Km ATP). Upon completion, the assay was stopped, and phosphorylated substrate detected with a te...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/25/2025
Entry Details
US Patent