BDBM746162 5-chloro-1-(1-(3-(methoxymethyl)bicyclo[1.1.1]pentan-1-yl)-1H-pyrazol-4-yl)-6-(4-(3-methyloxetan-3-yl)piperazin-1-yl)-1H-indazole::US12319671, Example 7.7

SMILES COCC12CC(n3cc(-n4ncc5cc(Cl)c(N6CCN(C7(C)COC7)CC6)cc54)cn3)(C1)C2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 746162   

LigandPNGBDBM746162(5-chloro-1-(1-(3-(methoxymethyl)bicyclo[1.1.1]pent...)
Affinity DataIC50: 90nMAssay Description:Inhibition of LRRK2 in human PBMCs assessed as Ser935 dephosphorylation incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM746162(5-chloro-1-(1-(3-(methoxymethyl)bicyclo[1.1.1]pent...)
Affinity DataIC50: 625nMAssay Description:Assays were performed in the presence of 134 μM ATP (Km ATP). Upon completion, the assay was stopped, and phosphorylated substrate detected with a te...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent