BDBM746167 5-chloro-1-{1-[3-(1- methoxyethyl)bicyclo [1.1.1]pentan-1-yl]-1H- pyrazol-4-yl}-6-[4-(3- methyloxetan-3- yl)piperazin-1-yl]-1H- indazole::US12319671, Example 7.12

SMILES COC(C)C12CC3(n4cc(-n5ncc6cc(Cl)c(N7CCN(C8(C)COC8)CC7)cc65)cn4)CC13C2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 746167   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM746167(5-chloro-1-{1-[3-(1- methoxyethyl)bicyclo [1.1.1]p...)
Affinity DataIC50: 625nMAssay Description:Assays were performed in the presence of 134 μM ATP (Km ATP). Upon completion, the assay was stopped, and phosphorylated substrate detected with a te...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/25/2025
Entry Details
US Patent