BDBM746182 1-[1-(bicyclo[1.1.1]pentan- 1-yl)-1H-pyrazol-4-yl]-5- chloro-6-{4-[(3R,4R or 3S,4S)-4-methoxy-3- methyloxolan-3- yl]piperazin-1-yl}-1H- indazole::US12319671, Example 10.2

SMILES CO[C@H]1COC[C@@]1(C)N1CCN(c2cc3c(cnn3-c3cnn(C45CC(C4)C5)c3)cc2Cl)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 746182   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM746182(1-[1-(bicyclo[1.1.1]pentan- 1-yl)-1H-pyrazol-4-yl]...)
Affinity DataIC50: 564nMAssay Description:Assays were performed in the presence of 134 μM ATP (Km ATP). Upon completion, the assay was stopped, and phosphorylated substrate detected with a te...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/25/2025
Entry Details
US Patent